Ambroxol hydrochloride


Introduction:
Product Name:    Ambroxol hydrochloride
Synonyms:  DURAMUCAL;LABOTEST-BB LT00134650;FLUIXOL;FRENOPECT;BLUIBRON;BRONCHOPRONT;ABRAMEN;AMBROXOL HYDROCHLORIDE
CAS:    23828-92-4
MF:    C13H19Br2ClN2O
MW:    414.56
EINECS:    245-899-2
Product Categories:  Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals;API's;Adrenoceptor;pharm grade;AMBROX;API;Inhibitors


Chemical Properties:
mp:     233-234.5°C
storage temp:     2-8°C
appearance: White Crystalline Powder


Safety Information:
Hazard Codes     Xn
Risk Statements     22
Safety Statements     36
WGK Germany     3
RTECS     GV8423000
HS Code     29221980


Usage:
1. expectorant
2. A metabolite of Bromohexine. Ambroxol Hydrochloride is a bronchosecretolytic drug.
3. skin whitening, depigmentation agent
4. Ambroxol is indicated as secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to brea


Biological Activity:
Sodium channel blocker and mucolytic agent with antioxidant, anti-viral and anti-inflammatory properties. resistant channels more potently than TTX-sensitive subtypes (IC 50 values for tonic block are 35.2 and 111.5 μ M respectively). Inhibits release of histamine, leukotrienes and cytokines from human leukocytes and mast cells.