Healthy Estrogen Blocking Supplements Betamethasone 378 - 44 - 9 White Powder
Quick Detail
Betamethasone
Product name: Betamethasone
CAS No.: 378-44-9
Assay: 99%
Molecular Formula: C22H29FO5
Molecular Weight: 392.461
Appearance: White or almost white crystalline powder
Molecular structure
Description:
Betamethasone, dexamethasone of isomers, the role and purpose with dexamethasone acetate, the sodium and water retention effect and dose than the latter is small. Glucose metabolism and anti-inflammatory effect than hydrocortisone strong as hydrocortisone 15 times, but the effect of sodium retention hydrocortisone hundred times more, in primary adrenal hypofunction in with glucocorticoid steroid replacement therapy used together. Also suitable for low renin and low aldosterone syndrome, autonomic neuropathy induced orthostatic hypotension. Because of the goods taken orally is prone to cause edema, more topically applying topical treatment for seborrheic eczema, contact dermatitis, anal, genital itching embolism. Mainly used for allergic and autoimmune inflammatory diseases. It is used for activities rheumatism, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, but also for the comprehensive treatment of certain infections.
Application:
1. Betamethasone is a corticosteroid used as a topical cream to relieve skin irritation, such as itching and flaking from eczema. It is used as a treatment for local psoriasis, as betamethasone dipropionate and
salicylic acid, or as the combination betamethasone/calcipotriol. Betamethasone sodium phosphate is
used orally and via injection with the same indications as other steroids.
2. Betamethasone is also used prior to delivery of a preterm baby to help prepare the lung for breathing
Specification:
Identification (B,C) |
Complies with the Standard |
Complies |
Specific optical Rotation |
+118°~+126° |
+123.5° |
Single impurity |
Not more than 1.0% |
0.29% |
impurity that ≥0.5% |
Not more than one |
Complies |
total impurities |
Not more than 2.0% |
0.64% |
Loss on drying |
Not more than 1.0% |
0.05% |
Assay(UV, basis on drying) |
97.0%~103.0% |
98.8% |
Methanol |
Not more than 3000ppm |
Complies |
Ethyl acetate |
Not more than 5000ppm |
Complies |
Acetone |
Not more than 5000ppm |
Complies |
DMF |
Not more than 880ppm |
Complies |
Dichloromethane |
Not more than 600ppm |
Complies |
Chloroform |
Not more than 60ppm |
Complies |
Particle Size |
100.0%<30um |
Complies |
Residue on ignition |
Not more than 0.2% |
0.03% |
Conclusion |
Qualified |