Product name:Hydrocortisone Acetate
Other name:Fluocinoloneacetate;dermalar;fluocinolone16,17-acetonide;
CAS No:50-03-3
Molecular formula:C23H32O6
Molecular weight:404.5
EINECS:200-004-4
Appearance: White crystalline powder
Catalogue:Pharmaceutical materials drug
|
Items of analysis |
Specification |
Results |
|
Appearance |
white or almost white, crystalline powder |
Almost white crystalline powder |
|
Identification |
IR/UV |
Conforms |
|
Specific optical rotation |
+158°~+167° |
+165° |
|
Loss on drying |
≤1.0% |
0.05% |
|
Residue on ignition |
≤0.5% |
0.2% |
|
Individual impurities |
≤1.0% |
0.16% |
|
Total Impurities |
≤2.0% |
0.41% |
|
pH(20mg/ml) |
Between 3.8 and 4.3 |
4.1 |
|
Acetone |
≤5000ppm |
ND |
|
Methanol |
≤3000ppm |
319ppm |
|
|
|
|
|
|
|
|
|
N,N-Dimethylformamide |
≤880ppm |
ND |
|
Assay |
97.0~102.0% |
99.1% |
|
Particle Size |
90%<30μm |
Conforms |
What is Hydrocortisone Acetate
Hydrocortisone Acetate, sold under the brandname Cortef among others, is the name for the hormone cortisol when supplied as a medication.Uses includes conditions such as adrenocortical insufficiency, adrenogenital syndrome, high blood calcium, thyroiditis, rheumatoid arthritis, dermatitis, asthma, and COPD. It is the treatment of choice for adrenocortical insufficiency. It can be given by mouth or by injection. After long-term use, if stopped this should be done slowly.
Hydrocortisone Acetate benefits:
This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Hydrocortisone acetate reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a mild corticosteroid.
How to use hydrocortisone acetate topical
Use this medication on the skin only. However, do not use it on the face, groin, or underarms unless directed to do so by your doctor.
Wash and dry your hands before using. Clean and dry the affected area. Apply a small amount of medication to the affected area and gently rub in, usually 2-4 times daily or as directed by your doctor. Do not bandage, cover, or wrap the area unless directed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants...
Side Effects of hydrocortisone acetate
(1)Stinging, burning, irritation, dryness, or redness at the application site may occur. Acne, excessive hair growth, "hair bumps" (folliculitis), skin thinning/discoloration, or stretch marks may also occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
(2)If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
(3)A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing...
China (Mainland)