(INN) is an anthracycline drug. An analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubiciM and exhibits activity against some doxorubiciM-resistant cell lines.
CAS:72496-41-4
MF:C32H37NO12
MW:627.6357