Etoricoxib
Name |
Etoricoxib |
Other Name |
Algix |
CAS No. |
202409-33-4 |
EINECS |
N/A |
MF |
C18H15ClN2O2S |
MW |
358.84 |
MP |
134-135°C |
Storage temp. |
-20°C Freezer |
Purity |
99% min |
Usage
For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
Description
Etoricoxib is indicated for the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain, and gout. Approved indications differ by country.
A Cochrane systematic review assessed the benefits of single-dose etoricoxib in reduction of acute post-operative pain in adults.Single-dose oral etoricoxib provides good quality pain relief post-operatively in adults and adverse events are similar to placebo in the studies included.Etoricoxib given at a dose of 120 mg is as effective or even better than other analgesics that are commonly used.
Anti-inflammatory painkillers like etoricoxib are sometimes called non-steroidal anti-inflammatory drugs (NSAIDs), or just 'anti-inflammatories'. Etoricoxib is used to treat painful conditions such as arthritis, gout and dental pain after surgery. It eases pain and reduces inflammation.
Etoricoxib is also known as a cyclo-oxygenase-2 inhibitor. This is because it works to relieve pain and inflammation by blocking an enzyme in the body called cyclo-oxygenase-2 (COX-2). COX-2 is involved in the production of irritant substances in the body in response to disease and injury. By blocking the action of COX-2, etoricoxib reduces the symptoms of pain and inflammation.
COA
Items |
Standards |
Results |
Appearance |
White to 0ff-white powder |
0ff-white powder
|
Residue on Ignition
|
≤0.1% |
0.074% |
Related substances
|
Single biggest impurity≤0.1%
Total impurities≤0.5%
|
0.01%
0.04%
|
Assay(HPLC) |
≥98%
|
99.9% |
Product Information
Etoricoxib is a selective COX-2 inhibitor, for the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain, and gout.