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CAS NO.30516-87-1
A(1-2)Kilogram
Zidovudine Usage And Synthesis |
Chemical Properties | Off White Crystalline Powder |
Usage | A potent and selective inhibitor of HIV-1 replication |
Usage | antibacterial |
General Description | Slightly off-white odorless powdery solid. |
Air & Water Reactions | Dust may form an explosive mixture in air. Water soluble. Hydrolysis occurs in strongly basic solutions . |
Reactivity Profile | Zidovudine is a azido compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. |
Fire Hazard | Flash point data for Zidovudine are not available; however, Zidovudine is probably combustible. |
Zidovudine Preparation Products And Raw materials |
Raw materials | Ethyl acetate-->Sodium azide-->Triphenylphosphine-->Formamide-->Anisic acid-->Diethyl azodicarboxylate-->Thymidine |