Lycoremine CAS 357-70-0 Galanthamine Hydrobromide for Alzheimer's Disease Treatment
Quick Detail of Galanthamine Hydrobromide
Product name: |
Galanthamine |
Other Name |
(4as,6r,8as)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6h-benzofuro[3a,3,2-ef][2]benzazepin-6-ol;GALANTAMINE;GALANTHAMINE;GALANTHAMINE HYDROCHLORIDE;6H-Benzofuro(3a,3,2-ef)(2)benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, (4aS-(4aalpha,6beta,8aR*))-;6h-benzofuro(3a,3,2-ef)(2)benzazepin-6-ol,4a,5,9,10,11,12-hexahydro-3-methox;Galantamin;Jilkon |
Original |
357-70-0 |
Molecular formula |
C17H21NO3 |
Molecular Weight |
287.35 |
Brand name |
NJBNSteroid |
Delivery time |
within 24 hours upon receipt of payment |
Delivery |
Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS |
Purity |
99% |
Package |
Discreet and Hidden package according to specific requirement |
Appearance |
Whire Powder |
Certification |
SGS, ISO 9001, KOSHER |
Payment Terms |
, Money Gram , T/T, Bitcoin |
Minimum Order Quantity |
10 g |
Price |
Negotiable |
Usage |
moderate Alzheimer's disease |
Description
Galanthamine,White or slightly yellow crystalline powder. Odorless, bitter taste. Melting point 127 ~ 129 ºC, [α] D20-118.8 ° (ethanol). Soluble in ethanol, acetone, chloroform, insoluble in benzene, ether and water. After reaction with ammonium molybdate solution, water bath, evaporate, sulfuric acid is added ,it turns to blue-green.
Use bulbs of Lycoris squamigera Maxim as raw material, under different acidity , extract and refine repeatedly with ethanol and chloroform to obtain the product . It belongs to anti-cholinesterase drugs.It is used for sequelae of infantile paralysis and myasthenia gravis. Medicinal use is its hydrobromide.
Alkaloids:
1. Galanthamine is alkaloid which is extracted from Amaryllidaceae plants Lycoris squamigera Maxim or Lycoris aurea,it is a reversible anti-cholinesterase drug, it is easy for it to go through the blood brain barrier into the brain tissue ,its effect on central nervous system is stronger.
2. it can improve neuromuscular conduction , compared with physostigmine, neostigmine , pyridostigmine , it has wide range of treatment, and low toxicity, muscarinic effects are weak and short-lived. Clinically Galanthamine is used not only for the treatment of myasthenia gravis, polio sequelae resting, but also for children with cerebral palsy, multiple neuritis, radiculitis and sensorimotor disorders caused by nervous system disease or trauma .