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Details
Product Description
Chemical information
Product Name: Fenbufen
Model No.: ANT-364
Appearance:White Solid
Suitable People:ALl
CAS No.: 36330-85-5
Molecular Formula: C16H14O3
Molecular Weight: 254.28
Melting Point:184-187 °C(lit.)
Product Specifications: Pharmaceutical Grade
Purity: 99%+
Standard:Qualified
MOQ(Minimum Order Quantity): 10g
Payment: Western Union
Shipment:EMS, DHL, FedEx, TNT
Packing: Foil Bag or as Required
Export Markets: Global
Product Description
Fenbufen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives class.
It was introduced by American Cyanamid under the trade name Lederfen in the 1980s and was withdrawn from markets in the developed world due to liver toxicity in 2010.:370, 383-384.As of 2015 is was available in Taiwan and Thailand under several brand names.
As a relatively new type of long-term non-steroidal anti-inflammatory and analgesic drug. According to animal studies, although the anti-inflammatory and analgesic action of this crystal was lower than those of indomethacin, but stronger than aspirin. Toxicity is smaller than indomethacin, gastrointestinal side effects than aspirin and other non-steroidal anti-inflammatory and analgesic drug. The pharmacological research showed that the crystal in the body metabolism into PCB ethyl ester, which inhibits the synthesis of prostaglandins, thereby blocking the role of inflammatory mediators, think this is this article main mechanism of anti-inflammatory effects. Finn cloth as a precursor of biphenyl ethyl ester, can avoid taking active metabolites directly after oral stimulation of the gastrointestinal tract. The domestic trial in rheumatoid arthritis, rheumatoid arthritis, the total effective rate was 87%. This drug is generally can make the chain of rheumatoid factor, blood sedimentation, turn back to normal or "O" and other indicators. Pathological examination did not see the main viscera have obvious pathological changes. Two hours after the oral blood concentrations of peak value. T 1/2 for 12 ~ 17 hours. Used for rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout treatment, etc. Also used for toothache, pain pain after surgery, trauma, pain, etc.
Dosage
Oral, adult 0.6 ~ 0.9 g a day, in a lump sum or by several times. Most of the patients in the evening a oral o. 6 g. By several times when taking daily must not exceed total o. 9 g.
Cycles
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