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keywords:Streptokinase,Rivaroxaban,CAS:366789-02-8,China GMP Standard Active Pharmaceutical Ingredient Fondaparinux Sodium,Find details about China Rivaroxaban,366789-02-8 from GMP Standard.
Rivaroxaban
Category: |
Pharmaceuticals and Biochemicals/Blood system agents |
|
CAS NO: |
366789-02-8 |
Molecular Formula: |
C19H18ClN3O5S |
Molecular Weight: |
435.8813 |
InChI: |
InChI=1/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1 |
Synonyms: |
5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide;Rivaroxaban intermediates;5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl]thiophene-2-carboxamide;rivaroxban; |
Rivaroxaban Usage:
Rivaroxaban can be used to prevent strokes in those with atrial fibrillation due to causes other than heart valve disease, and at least one additional risk factor for stroke (congestive heart failure, hypertension, age, diabetes, and prior stroke).
Rivaroxaban can also be used to prevent the formation of blood clots in the veins in adults who have had an operation to replace a hip or knee and following an acute deep venous thrombosis in adults.
Rivaroxaban Applications:
Rivaroxaban can be used to prevent strokes in those with atrial fibrillation due to causes other than heart valvedisease, and at least one additional risk factor for stroke (congestive heart failure, hypertension, age, diabetes, and prior stroke)
Rivaroxaban can also be used to prevent the formation of blood clots in the veins (deep venous thrombosis) in adults who have had an operation to replace a hip or knee and for treatment and prevention of acute deep venous thrombosis in adults. It can not be used for prevention of venous thrombosis in hospitalized medically ill patients.
Rivaroxaban is not indicated for prosthetic heart valves or for mitral stenosis.
Rivaroxaban is not indicated as an add-on treatment for dual antiplatelet therapy in the secondary prevention of coronary incidents (double and triple therapy). In Europe, however, a 2.5-mg twice-daily dose was approved by the European Commission after a recommendation by the European Medicines Agency (EMA) for the prevention of atherothrombotic events in adult patients after an acute coronary syndrome (ACS) with elevated cardiac biomarkers co-administered with acetylsalicylic acid (ASA) alone or with ASA plus clopidogrel or ticlopidine.