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Country: China (Mainland)
Business Type:Trading Company
CAS NO.439081-18-2
A(1-2)Kilogram
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Product Name: Afatinib powder
CAS No.: 439081-18-2
EINECS: N/A
Molecular Weight: 485.944
Molecular Formula: C24H25ClFN5O3
Melting Point(°C): 213-215°C
Specification
Appearance |
White to off-white powder |
Complies |
Identification |
H-NMR |
Complies |
Purity(by HPLC) |
Not less than 99.0% |
99.47% |
Loss on dry |
Not more than 0.5% |
0.25% |
Single impurity |
Not more than 1.0% |
0.32% |
Conclusion |
The batch complies with In-house standard. |
Afatinib (English name: Afatinib), is a kind of innovative anti-cancer targeted therapy, which is a new generation of oral targeted drugs, is the first in the world of irreversible binding to the ErbB family (including four kinds of cancer cells in different epidermal growth factor receptor, such as EGFR, HER2, ErbB3 and ErbB4) anticancer standard the target drug, and more effectively and to block the growth of cancer cells caused by signal, reduce or delay the proliferation of cancer cells.
Afatinib has been in the United States, Europe and Taiwan approved national area used as first-line therapy, has been applied to the epidermal growth factor receptor (English: EGFR) mutations of non-small cell lung cancer cancer cells (English: NSCLC) is a daily oral treatment, the targeted therapy drug。
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